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In addition to dose, other factors that affect the quantity of live bacteria that enter the intestine include formulation, gastric pH, intestinal motility, co-administration with food or milk (which protects against gastric acid), and the makeup of an individuals gut microbiota

glutathione helps neutralize these harmful effects

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Nutrition 29(5):713718 Kieliszek M, Baejak S, Bzducha-Wrbel A, Kot AM (2019) Effect of selenium on lipid and amino acid metabolism in yeast cells